【Objective】the present experiment was conducted to evaluate and analyze the seasonal variation of water quality in Megalobrama amblycephala culture area， in order to provide scientific basis for building healthy culture model. 【Method】Annual water quality changes of water source， impounding reservoir and intensive culture ponds were monitored in Megalobrama amblycephala culture area. The major indexes were determined， including temperature（T）， pH， dissolved oxygen（DO）， transparency（SD）， total phosphorus（TP）， total nitrogen（TN）， ammonium nitrogen（NH3-N）， nitrite nitrogen（NO2--N）， permanganate index（CODMn） and chlorophyll a（Chla）. 【Result】the results showed that some differences of SD and NH3-N of water source were not found significant， but significant differences existed among other indexes in different seasons， and the pros and cons water quality in order was summer＞autumn＞spring＞winter; significant differences existed among the whole indexes of impounding reservoir in different seasons， the pros and cons water quality in order was autumn＞winter＞spring＞summer; some differences were not found significant for pH， DO， SD， CODMn and Chla of intensive culture pond， but significant differences existed among other indexes between winter and summer， the pros and cons water quality in order was autumn＞spring＞summer＞winter. Water body of culture area was eutrophicated， especially intensive culture pond was hyper-eutrophicated. 【Conclusion】Water quality of Megalobrama amblycephala culture area are Ⅳ-Ⅴ grades mostly and eutrophicated seriously， and it should be paid more attention to the management of water quality especially during winter， and water can be purified by planting hydrophyte.